BDBM50407460 CHEMBL4175379

SMILES CC(C)Oc1cc(ccc1NC(=O)c1[nH]c(C)c(Cl)c1Cl)C(=O)N[C@H](C)C(O)=O

InChI Key InChIKey=TWXFDOYZBJAPPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50407460   

TargetDNA gyrase subunit B(Staphylococcus aureus)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50407460(CHEMBL4175379)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B preincubated for 10 mins followed by ATP addition measured after 30 mins by purine nucleoside phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50407460(CHEMBL4175379)
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed