BDBM50407426 CHEMBL5271210

SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)CN(CCC1CCN(Cc3ccccc3)CC1)C2=O)c1ccc2OCOc2c1

InChI Key InChIKey=KVANOXIAOYTXBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50407426   

TargetAcetylcholinesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407426(CHEMBL5271210)
Affinity DataIC50: 32nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407426(CHEMBL5271210)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50407426(CHEMBL5271210)
Affinity DataIC50: 32nMAssay Description:Inhibition of PDE5A1 (unknown origin) using FAM-cGMP as substrate incubated for 60 mins by IMAP-fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Rat)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407426(CHEMBL5271210)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate incubated for 20 mins by DTNB-reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed