BDBM50406883 CHEMBL4177432

SMILES c1ccc2c(c1)nc(c(n2)Nc3cccc(c3)O)C(=O)O

InChI Key InChIKey=BGYMHNWAGXBGBJ-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50406883   

TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain GSK-3alpha/beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrate after 30 mins by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacterial expression system using GRSRSRSRSRSR as substrate after 30 mins by ADP-Glo reagent based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human haspin kinase domain (470 to 798 residues) expressed in bacterial expression system using histone H3 peptide as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CDK9/CyclinT expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK2/CyclinA using histone H1 as substrate after 30 mins by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain (1 to 499 residues) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50406883(CHEMBL4177432)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant human Pim1 expressed in bacterial expression system using histone H1 as substrate after 30 mins by ADP-Glo reagent based lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)