BDBM50406768 CHEMBL288821

SMILES NCCc1c[nH]c2ccc(cc12)-c1nc(Cc2ccccc2)no1

InChI Key InChIKey=ODYUGGSOAUEDQI-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50406768   

Target5-hydroxytryptamine receptor 1D(Pig)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406768(CHEMBL288821)
Affinity DataIC50: 6.30nMAssay Description:Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406768(CHEMBL288821)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from pig cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406768(CHEMBL288821)
Affinity DataIC50: 3.98E+3nMAssay Description:Displacement of [3H]mesulergine from pig cortex 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406768(CHEMBL288821)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-Q-ICS 205-930 from rat cortex homogenate 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406768(CHEMBL288821)
Affinity DataIC50: 1.26E+3nMAssay Description:isplacement of [3H]DOB from rat cortex homogenate 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed