BDBM50406179 CHEMBL4166609

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(Nc2ccccc2-n2cccn2)n1

InChI Key InChIKey=XWFQQRHKIANCBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50406179   

TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406179(CHEMBL4166609)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406179(CHEMBL4166609)
Affinity DataIC50: 648nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed