BDBM50405982 CHEMBL56602

SMILES Cc1cc(C)cc(Cc2cnc(N)nc2N)c1

InChI Key InChIKey=RJRSBERDOBVYQI-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50405982   

TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataIC50: 35nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataKi:  8.90nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Salmonella typhi)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataKi:  91nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataKi:  1.35E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataKi:  2.45E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed