BDBM50405913 CHEMBL4176916

SMILES Cc1cc(Br)cc2C(=O)NC(Nc12)c1c[nH]nc1-c1cccc2ccccc12

InChI Key InChIKey=HMTOXAAOXBALFX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50405913   

TargetTransient receptor potential cation channel subfamily M member 2(Human)
Peking University

Curated by ChEMBL

LigandBDBM50405913(CHEMBL4176916)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced channel currents treated extracellularly after 60 secs by w...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily M member 2(Human)
Peking University

Curated by ChEMBL

LigandBDBM50405913(CHEMBL4176916)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL