BDBM50405753 CHEMBL5274634

SMILES ONC(=O)c1ccc(Cn2cnc(n2)-c2ccccc2F)c(F)c1

InChI Key InChIKey=WTKSXRWOROTBGM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50405753   

TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant HDAC6 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 299nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 299nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 509nMAssay Description:Inhibition of human recombinant HDAC2 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of human recombinant HDAC4 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 813nMAssay Description:Inhibition of human recombinant HDAC8 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50405753(CHEMBL5274634)
Affinity DataIC50: 8.09E+3nMAssay Description:Inhibition of human recombinant HDAC11 using fluorogenic substrate measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed