BDBM50405636 CHEMBL5282715

SMILES Cc1nc(-c2ccccc2)c([nH]c1=O)-c1ccc(CN2CCC(CC2)n2c3cc(NC(=O)C=C)ccc3[nH]c2=O)cc1

InChI Key InChIKey=CGWRGCGZPRWFTG-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50405636   

TargetRAC-alpha serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405636(CHEMBL5282715)
Affinity DataIC50: 39nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405636(CHEMBL5282715)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50405636(CHEMBL5282715)
Affinity DataIC50: 1.30E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
TU Dortmund University and Drug Discovery Hub Dortmund (DDHD)

Curated by ChEMBL
LigandPNGBDBM50405636(CHEMBL5282715)
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405636(CHEMBL5282715)
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed