BDBM50405634 VEVORISERTIB::Vevorisertib

SMILES CN(C1CCN(CC1)c1cccc(c1)-c1ccc2nc(-c3cccnc3N)n(-c3ccc(cc3)C3(N)CCC3)c2n1)C(C)=O

InChI Key InChIKey=NZDSLYATTDIDPH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405634   

TargetRAC-alpha serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405634(VEVORISERTIB | Vevorisertib)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405634(VEVORISERTIB | Vevorisertib)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of AKT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405634(VEVORISERTIB | Vevorisertib)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of AKT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed