BDBM50405629 CHEMBL5278435

SMILES COc1ccc(cc1)C(=O)NNC(=O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1

InChI Key InChIKey=AIGSGJXYLHDMBA-UHFFFAOYSA-N

Data  8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50405629   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 0.460nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 55nMAssay Description:Inhibition of P13Kbeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of P13Kgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 32nMAssay Description:Inhibition of P13Kdelta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetSerine/threonine-protein kinase mTOR(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 3.80nMAssay Description:Inhibition of PKB phosphorylation in human SK-OV-3 cells incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL

TargetSerine/threonine-protein kinase mTOR(Human)
University of Calabria

Curated by ChEMBL

LigandBDBM50405629(CHEMBL5278435)Copy SMILESCopy InChI

Affinity DataIC50: 0.460nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL