BDBM50405464 CHEMBL5270743

SMILES [H][C@@]1(C[C@H](NC(=O)[C@H]2N(C[C@]3([H])CCC[C@]23[H])C(=O)COc2ccc(Cl)cc2Cl)C=O)CCNC1=O

InChI Key InChIKey=HKJKOHDJUKCNRG-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50405464   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 17nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 17nMAssay Description:Inhibition of SARS-CoV-2 Main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 40nMAssay Description:Inhibition of His/SUMO tagged SARS-CoV-2 main protease transfected in Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKME-Edans as substrate prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataEC50:  650nMAssay Description:Inhibition of eGFP-fused SARS-CoV-2 main protease transfected in HEK293T/17 cells incubated for 3 days by flow cytometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed