BDBM50405453 CHEMBL5271309

SMILES CC(O)[C@H](NCc1cc2C(=O)N(C(=O)c2cc1OCc1cccc(c1)C#N)c1cccc(c1C)-c1ccccc1)C(O)=O

InChI Key InChIKey=KFUYSOVWQASPQA-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50405453   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Acharya & Bm Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50405453(CHEMBL5271309)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human PD-1/PDL1 protein-protein interaction by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Acharya & Bm Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50405453(CHEMBL5271309)
Affinity DataKd:  24nMAssay Description:Binding affinity to human PDL1 assessed as dissociation constant by MST methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Acharya & Bm Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50405453(CHEMBL5271309)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) protein-protein interaction incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Acharya & Bm Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50405453(CHEMBL5271309)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PD-I/PD-L1 interaction (unknown origin) incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed