BDBM50405285 CHEMBL5269317

SMILES COc1ccc2cc1Nc1nccc(n1)-c1cn(CCCCCCN2C(=O)C=C)c2ccccc12

InChI Key InChIKey=XJXDTLCWUFYVIB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405285   

TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed