BDBM50405216 CHEMBL5290029

SMILES Nc1ncncc1-c1ccnc2n(ncc12)-c1ccc(F)cc1

InChI Key InChIKey=OEVSKJAZBGCGII-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50405216   

TargetSteroid 21-hydroxylase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP21A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP2B6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2C8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human CYP11B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Crab-eating macaque)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 2nMAssay Description:Inhibition of cynomolgus monkey adrenal gland CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 30nMAssay Description:Inhibition of human adrenal gland CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Crab-eating macaque)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 30nMAssay Description:Inhibition of cynomolgus monkey CYP17A1 hydroxylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Crab-eating macaque)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 6nMAssay Description:Inhibition of cynomolgus monkey CYP17A1 lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 91nMAssay Description:Inhibition of human CYP17A1 hydroxylase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 8nMAssay Description:Inhibition of human CYP17A1 lyase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Crab-eating macaque)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 2nMAssay Description:Inhibition of cynomolgus monkey CYP17A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50405216(CHEMBL5290029)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed