BDBM50405190 CHEMBL2028991

SMILES CC(C)C[C@H](NC(=O)CC(O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=ZOAVSRHEYNKAIW-UHFFFAOYSA-N

Data  10 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50405190   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.160nMAssay Description:Inhibition of human kidney reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.190nMAssay Description:The compound was tested for inhibition of rhesus monkey plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  0.540nMAssay Description:The compound was tested for inhibition of rabbit plasma renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  3.70nMAssay Description:The compound was tested for inhibition of hog kidney renin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  21nMpH: 7.4Assay Description:The compound was tested for inhibition of rat plasma renin at pH of 7.4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  27nMAssay Description:The compound was tested for inhibition of rabbit liver cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  28nMAssay Description:The compound was tested for inhibition of porcine pepsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Bread mold)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  230nMpH: 7.4Assay Description:The compound was tested for inhibition of rat plasma renin at pH of 7.4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetRenin(Bread mold)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  230nMAssay Description:Inhibition of rhizopuspepsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50405190(CHEMBL2028991)
Affinity DataKi:  1.20E+4nMAssay Description:The compound was tested for inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed