BDBM50404889 CHEMBL303714

SMILES c1ccc2c(c1)[nH]c(n2)CN

InChI Key InChIKey=UCOSRTUSVXHIMK-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404889   

TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: 4.57E+5nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase in cell free Quan-T-RT by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetStromelysin-3(Mouse)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50404889(CHEMBL303714)
Affinity DataIC50: 0.0280nMAssay Description:Cytotoxicity against human NB-1 cells by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed