BDBM50404379 CHEMBL5184599

SMILES [H][C@@]12CCC[C@]1([H])[C@H](N(C2)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnc(cn1)C(=O)NCCOCCOCCOc1cc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c3cccc(c1)c23)C1CCCCC1)C(C)(C)C)C(=O)N[C@@H](CCC)C(=O)C(=O)NC1CC1

InChI Key InChIKey=YZNSNVPSBDWZBQ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50404379   

TargetProtein cereblon(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404379(CHEMBL5184599)
Affinity DataEC50:  703nMAssay Description:Displacement of dBET6 from CRBN (unknown origin) transfected in BRD4 BD2-GFP mCherry report cells incubated for 5 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404379(CHEMBL5184599)
Affinity DataIC50: 247nMAssay Description:Inhibition of HCV NS3/4a protease in Huh7.5 SGR cells using [Ac-DE-D(Edans)-EE-Abu-[COO]AS-K(Dabcyl)-NH2] as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed