BDBM50404156 CHEMBL5272243

SMILES COc1ccc(cc1)-c1oc2cc(Br)c(I)cc2c(=O)c1O

InChI Key InChIKey=AYKASAIWJOBKAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50404156   

TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50: 16nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of BACE-1(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant human BACE-1 expressed in baculovirus using Rh-EVNLDAEFK-Quencher as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Aveiro

Curated by ChEMBL
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50: 29nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed