BDBM50404071 CHEMBL5268667

SMILES C=CC(=O)Nc1ccnc2ccccc12

InChI Key InChIKey=FIHXAIFDJPVFAT-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50404071   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of wild type SHP2 PTP domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of 6xHis-tagged human PTP1B catalytic domain using pNPP as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human His6-tagged wild type SHP2 PTP domain using pNPP as substrate by absorbance based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404071BDBM50404071(CHEMBL5268667)
Affinity DataKi:  2.79E+5nMAssay Description:Binding affinity to SHP2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed