BDBM50404037 CHEMBL5287302

SMILES C[C@H](NS(=O)(=O)c1cccc(NC(=O)c2ccc(NC(CO)CO)nc2N2CCC3(CC3)CC2)c1)C(F)(F)F

InChI Key InChIKey=WVFKLBXKVKFORP-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50404037   

TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50404037(CHEMBL5287302)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50404037(CHEMBL5287302)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to KIF18A (unknown origin) by NMR based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50404037(CHEMBL5287302)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of KIF18A ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed