BDBM50404013 CHEMBL2112677

SMILES COCc1cccc(c1)C#Cc1cccc(C)n1

InChI Key InChIKey=OCPXWGYPEFSLKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50404013   

TargetMetabotropic glutamate receptor 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50404013(CHEMBL2112677)
Affinity DataIC50: 3.60nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50404013(CHEMBL2112677)
Affinity DataIC50: 7nMAssay Description:In vitro functional potency using an automated assay employing LtK-cells stably expressing human recombinant mGlu5 receptor by measuring changes in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50404013(CHEMBL2112677)
Affinity DataIC50: 10nMAssay Description:In vitro for inhibitory activity of compound against recombinant Metabotropic glutamate receptor 5 evaluated as inhibition of quisqualate-stimulated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed