BDBM50403825 CHEMBL2111955

SMILES Cc1cc(C)cc(c1)-c1c(OCC[C@@H]2CCCCN2)c2cc(C(=O)Nc3cnsn3)c(Cl)cc2[nH]c1=O

InChI Key InChIKey=CCMNSLGQHAOUGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403825   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403825(CHEMBL2111955)
Affinity DataIC50: 24nMAssay Description:In vitro inhibition of GnRH stimulated release of luteinizing hormone from the rat primary pituitary cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403825(CHEMBL2111955)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403825(CHEMBL2111955)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells stably expressing gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed