BDBM50403727 CHEMBL2112310

SMILES CC[C@@H]1CNc2cc3oc(=O)cc(c3cc2[C@H]1CC)C(F)(F)F

InChI Key InChIKey=ABMNASWKARFNAA-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50403727   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataEC50:  1.40E+3nMAssay Description:In vitro antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro antagonistic activity against human mineralocorticoid receptor (hMR); not activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataIC50: 65nMAssay Description:In vitro antagonistic activity against human progesterone receptor (hPR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro antagonistic activity against human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonistic activity against human estrogen receptor (hER); Not activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataEC50:  5nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed