BDBM50403713 CHEMBL2092731

SMILES CSCC[C@@H](NC(=O)[C@H]1C[C@@H](CN1C\C=C\[C@@H](N)CS)Oc1ccccc1)C(O)=O

InChI Key InChIKey=GZFFUOZMNSMHSN-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403713   

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Eisai Research Institute

Curated by ChEMBL

LigandBDBM50403713(CHEMBL2092731)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/30/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Eisai Research Institute

Curated by ChEMBL

LigandBDBM50403713(CHEMBL2092731)Copy SMILESCopy InChI

Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/30/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL