BDBM50403672 CHEMBL24665

SMILES NCCc1cnc([nH]1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=NFUYVKMAGIJYKB-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50403672   

TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50403672(CHEMBL24665)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against human Histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Freie Universit£T Berlin

Curated by ChEMBL
LigandPNGBDBM50403672(CHEMBL24665)
Affinity DataEC50:  1.28E+3nMAssay Description:H1-Histamine receptor agonism on Guinea pig aorta was evaluated (SEM 0.03-0.18)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50403672(CHEMBL24665)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50403672(CHEMBL24665)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50403672(CHEMBL24665)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed