BDBM50403650 CHEMBL4162888

SMILES CC(C)c1cc(-c2onc(C(=O)NCC(=O)Nc3cccc(Nc4ncc(Cl)c(Nc5ccccc5S(=O)(=O)C(C)C)n4)c3)c2-c2ccc(CN3CCOCC3)cc2)c(O)cc1O

InChI Key InChIKey=WGVGJODPUDQOKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403650   

TargetHeat shock protein HSP 90-alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403650(CHEMBL4162888)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FITC-labeled geldanamycin binding to recombinant HSP90alpha (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50403650(CHEMBL4162888)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed