BDBM50403554 CHEMBL5282512

SMILES O=C(Nc1cccc(c1)S(=O)(=O)C1CCCC1)c1cccnc1N1CCCCC1

InChI Key InChIKey=PGNDBHSSJBNDJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50403554   

TargetKinesin-like protein KIF18A(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403554(CHEMBL5282512)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403554(CHEMBL5282512)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human Eg5 assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCentromere-associated protein E(Human)
Amgen Research

Curated by ChEMBL
LigandPNGBDBM50403554(CHEMBL5282512)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant GST-tagged human CENP-E assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed