BDBM50403297 CHEMBL5288854

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2cnc3[C@H](C(C)C)N(C[C@H]4CC[C@@H](CC4)C(F)(F)F)Cc3c2)nc1

InChI Key InChIKey=KEKCGMLTBGENHB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403297   

TargetInterleukin-17A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403297(CHEMBL5288854)
Affinity DataIC50: 221nMAssay Description:Inhibition of human IL-17 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50403297(CHEMBL5288854)
Affinity DataKi:  3.70nMAssay Description:Displacement of 25-[26,27-3H2]-hydroxycholesterol from RORgammat (unknown origin) assessed as inhibition constant by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed