BDBM50403067 CHEMBL2216876::US20250170122, Compound 7

SMILES Cc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc23)cc2cccc(C)c2c1=O

InChI Key InChIKey=XWHQPBKSJATHQB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50403067   

LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3Kdelta by cell-based proliferation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM50403067(CHEMBL2216876 | US20250170122, Compound 7)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2025
Entry Details
Go to US Patent