BDBM50403062 CHEMBL2216857

SMILES Cn1cc(cn1)-c1ccc2OCCN(C3=NC4CC(C)(C)NC(=O)C4S3)c2c1

InChI Key InChIKey=JYDJBPGMWFAOJP-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403062   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen

Curated by ChEMBL

LigandBDBM50403062(CHEMBL2216857)Copy SMILESCopy InChI

Affinity DataIC50: 111nMAssay Description:Inhibition of PI3Kdelta in neutrophil assessed as inhibition of superoxide production by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen

Curated by ChEMBL

LigandBDBM50403062(CHEMBL2216857)Copy SMILESCopy InChI

Affinity DataIC50: 32nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL