BDBM50402996 CHEMBL2207440

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(n[nH]1)-c1ccc2ncccc2c1)C(C)(C)C

InChI Key InChIKey=KQLHECVWPJTIGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402996   

TargetFocal adhesion kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50: 608nMAssay Description:Inhibition of FAK after 2hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50: 98nMAssay Description:Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50402996(CHEMBL2207440)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed