BDBM50402687 CHEMBL2207363

SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3nnn[nH]3)c2)cc1

InChI Key InChIKey=JFFMSCZODNPVKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402687   

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50402687(CHEMBL2207363)
Affinity DataIC50: 81nMAssay Description:Apparent inhibition of recombinant human FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50402687(CHEMBL2207363)
Affinity DataIC50: 46nMAssay Description:Apparent inhibition of recombinant rat FAAH expressed in SK-N-MC cells assessed as [3H]-anandamide hydrolysis after 1 hr by liquid scintillation anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50402687(CHEMBL2207363)
Affinity DataIC50: 46nMAssay Description:Inhibition of rat FAAH preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50402687(CHEMBL2207363)
Affinity DataIC50: 103nMAssay Description:Inhibition of human FAAH preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed