BDBM50402419 CHEMBL2207764

SMILES CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2cccc(NC(=O)c3c(Cl)cccc3Cl)c2)n1

InChI Key InChIKey=YJLSAFWTHWLPPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402419   

TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)
Affinity DataIC50: 505nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)
Affinity DataIC50: 763nMAssay Description:Inhibition of JAK2 in HEL 92.1.7 cells assessed as inhibition of STAT1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)
Affinity DataIC50: 980nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50402419(CHEMBL2207764)
Affinity DataIC50: 12.6nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed