BDBM50402336 CHEMBL2206107

SMILES Cn1c(SCCc2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=LXNLGYHPWSMVIH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402336   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50402336(CHEMBL2206107)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cell microsome assessed as 4-hydroxyquinoline formation using kynuramine as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50402336(CHEMBL2206107)
Affinity DataIC50: 8.46E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cell microsome assessed as 4-hydroxyquinoline formation using kynuramine as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50402336(CHEMBL2206107)
Affinity DataKi:  9.80nMAssay Description:Competitive inhibition of human recombinant MAO-B expressed in insect cell microsome using kynuramine as substrate by Morrison equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50402336(CHEMBL2206107)
Affinity DataKi:  13nMAssay Description:Competitive inhibition of human recombinant MAO-B expressed in insect cell microsome using kynuramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed