BDBM50402264 CHEMBL2204779

SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Nc2cccc(c2)C(O)=O)o1

InChI Key InChIKey=FSPSBPWQYZGGSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402264   

LigandPNGBDBM50402264(CHEMBL2204779)
Affinity DataIC50: 12nMAssay Description:Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50402264(CHEMBL2204779)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50402264(CHEMBL2204779)
Affinity DataIC50: 328nMAssay Description:Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed