BDBM50402258 CHEMBL2204784

SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(Oc2cccnc2)o1

InChI Key InChIKey=RLCMKGIYRDAFFS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402258   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Taisho Pharmaceutical

Curated by ChEMBL

LigandBDBM50402258(CHEMBL2204784)Copy SMILESCopy InChI

Affinity DataIC50: 117nMAssay Description:Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Mouse)
Taisho Pharmaceutical

Curated by ChEMBL

LigandBDBM50402258(CHEMBL2204784)Copy SMILESCopy InChI

Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL