BDBM50402254 CHEMBL2204788

SMILES CC(=O)Nc1nc(C)c(s1)-c1cnc(CC(F)(F)F)o1

InChI Key InChIKey=UULIVRWXUZHWBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402254   

LigandPNGBDBM50402254(CHEMBL2204788)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PI3Kgamma using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50402254(CHEMBL2204788)
Affinity DataIC50: 88nMAssay Description:Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as inhibition of C5a-induced PKB/Akt phosphorylation incubated for 30 mins prior to C5a-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50402254(CHEMBL2204788)
Affinity DataIC50: 43nMAssay Description:Inhibition of human PI3Kalpha using phosphatidylinositol as substrate and [33gammaP]ATP after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed