BDBM50401849 CHEMBL2204663

SMILES CCn1cc2c(Oc3cnc(C(=O)N4CCC4)c(F)c3)cc(cc2n1)C(=O)Nc1cnc(C)cn1

InChI Key InChIKey=VRBFJTUHFBTQRQ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401849   

TargetHexokinase-4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401849(CHEMBL2204663)
Affinity DataEC50:  350nMAssay Description:Activation of recombinant rat glucokinase assessed measuring rate of glucose 6-phosphate formation using G6PDH/NADP couplingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401849(CHEMBL2204663)
Affinity DataEC50:  120nMAssay Description:Activation of recombinant human glucokinase assessed measuring rate of glucose 6-phosphate formation using G6PDH/NADP couplingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50401849(CHEMBL2204663)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed