BDBM504017 (1R,2R)-N-[8-amino-6-(5-hydroxy-2- methylphenyl)-2,7-naphthyridin-3-yl]-2- (1-methyl-1H-pyrazol-4-yl)cyclopropane- 1-carboxamide::US11034692, Compound 287

SMILES Cc1ccc(O)cc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3c3cnn(C)c3)ncc2c(N)n1

InChI Key InChIKey=HPJXSTKOZQAULW-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504017   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM504017((1R,2R)-N-[8-amino-6-(5-hydroxy-2- methylphenyl)-2...)Copy SMILESCopy InChI

Affinity DataKi:  0.0780nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/5/2021
Entry Details
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