BDBM50401481 CHEMBL2204572

SMILES CC[C@H](NC)C(=O)N[C@H]1[C@@H](CNC(=O)c2cn(C[C@H]3CC[C@H]4CC[C@H](N4C(=O)[C@H]3NC(=O)[C@H](CC)NC)C(=O)NC(c3ccccc3)c3ccccc3)nn2)CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=XQDCNKGNHWZJNL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401481   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401481(CHEMBL2204572)
Affinity DataIC50: 15.5nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401481(CHEMBL2204572)
Affinity DataIC50: 244nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401481(CHEMBL2204572)
Affinity DataIC50: 1.70nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed