BDBM50401480 CHEMBL2204571

SMILES CN[C@@H](C)C(=O)N[C@@H]([C@H](C)OCC#CC#CCO[C@@H](C)[C@H](NC(=O)[C@H](C)NC)C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1)C(=O)N1CCC[C@H]1Cn1nnnc1Sc1ccccc1

InChI Key InChIKey=CDUYVSXKBIKUNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401480   

TargetE3 ubiquitin-protein ligase XIAP(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401480(CHEMBL2204571)
Affinity DataIC50: 3.30nMAssay Description:Displacement of Smac-1F from human His-tagged XIAP linker BIR2-BIR3 linker (124 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401480(CHEMBL2204571)
Affinity DataIC50: 80.7nMAssay Description:Displacement of FITC-Smac from human His-tagged XIAP BIR3 domain (241 to 356 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Fondazione Irccs Istituto Nazionale Dei Tumori

Curated by ChEMBL
LigandPNGBDBM50401480(CHEMBL2204571)
Affinity DataIC50: 12.6nMAssay Description:Displacement of FITC-Smac from human recombinant His-tagged cIAP-1 BIR3 domain (245 to 357 residues) after 3 hrs by fluorescent polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed