BDBM50401471 CHEMBL243810

SMILES O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1

InChI Key InChIKey=UCEVYDVOUKTNMU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50401471   

TargetDNA-dependent protein kinase catalytic subunit(Human)
La Trobe University

Curated by ChEMBL
LigandPNGBDBM50401471(CHEMBL243810)
Affinity DataIC50: 300nMAssay Description:Inhibition of DNA-PK using EPPLSQEAFADLWKK as substrate after 5 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50401471(CHEMBL243810)
Affinity DataIC50: 950nMAssay Description:Inhibition of PI3Kdelta by HTRF assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50401471(CHEMBL243810)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PI3Kgamma by HTRF assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50401471(CHEMBL243810)
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of PI3Kbeta by HTRF assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50401471(CHEMBL243810)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of PI3Kalpha by HTRF assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed