BDBM50401450 CHEMBL2204552

SMILES Nc1ccc(c(F)c1)-c1cccc2c1oc(nc2=O)N1CCOCC1

InChI Key InChIKey=UNKSAIJHKLOVQP-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401450   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50401450(CHEMBL2204552)Copy SMILESCopy InChI

Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of PI3Kgamma by HTRF assay in presence of ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50401450(CHEMBL2204552)Copy SMILESCopy InChI

Affinity DataIC50: 540nMAssay Description:Inhibition of PI3Kbeta by HTRF assay in presence of ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
La Trobe University

Curated by ChEMBL

LigandBDBM50401450(CHEMBL2204552)Copy SMILESCopy InChI

Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of PI3Kalpha by HTRF assay in presence of ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL