BDBM50401438 CHEMBL2203775

SMILES CN1CCN(CC1)c1cccc(c1)-c1nc2ncc(Cl)c(N3CCN(Cc4cc(C)on4)CC3)c2[nH]1

InChI Key InChIKey=ROFVRNNNZDBODT-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401438   

TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401438(CHEMBL2203775)
Affinity DataIC50: 26nMAssay Description:Binding affinity to Aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401438(CHEMBL2203775)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human ERG by whole-cell voltage clampingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50401438(CHEMBL2203775)
Affinity DataKd:  5.40nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed