BDBM50401302 CHEMBL2205203::US8492392, 1-7

SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(OC4CCN(C)CC4)c3C2)-c2cccnc2)c1

InChI Key InChIKey=YNSNONPSWODZFE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50401302   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50401302(CHEMBL2205203 | US8492392, 1-7)
Affinity DataKi:  14nM ΔG°:  -10.7kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50401302(CHEMBL2205203 | US8492392, 1-7)
Affinity DataKi:  14nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed