BDBM50401085 CHEMBL2204446

SMILES COc1ccc(cc1)C#Cc1ccc(cc1)C(=O)N1CCC[C@H](CO)C1

InChI Key InChIKey=VSLWUPHHCFQTDB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50401085   

TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50401085(CHEMBL2204446)
Affinity DataIC50: 5.49E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50401085(CHEMBL2204446)
Affinity DataIC50: 2.10E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50401085(CHEMBL2204446)
Affinity DataIC50: 3.24E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50401085(CHEMBL2204446)
Affinity DataIC50: 2.04E+3nMAssay Description:Negative allosteric modulation of mGlu3 assessed as thallium flux through GIRK channels by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50401085(CHEMBL2204446)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed