BDBM50401005 CHEMBL2206290

SMILES CN(C[C@H]1C[C@@H](C1)c1ccc(CN2CCCC2)c(Cl)c1)C(C)=O

InChI Key InChIKey=LQOGSAVOXSCLHL-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50401005   

TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  3.30nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP release pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  3.31nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP release pretreate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  12.9nMAssay Description:Displacement of [3H]-n-alpha-methylhistamine from human histamine H3 receptor homogenate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-n-alpha-methylhistamine from human histamine H3 receptor homogenate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  20.9nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP release pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  21nMAssay Description:Antagonist activity at rat histamine H3 receptor expressed in human HEK293 cells assessed as inhibition of forskolin-induced cAMP release pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]-n-alpha-methylhistamine from rat histamine H3 receptor homogenate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50401005(CHEMBL2206290)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-n-alpha-methylhistamine from rat histamine H3 receptor homogenate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed