BDBM50400735 CHEMBL2203537

SMILES CN1C(=S)NC(=O)\C(=C/c2c[nH]c3ccccc23)C1=O

InChI Key InChIKey=JAEFLVKCBWNJSP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400735   

LigandPNGBDBM50400735(CHEMBL2203537)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400735(CHEMBL2203537)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50400735(CHEMBL2203537)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of p300 (unknown origin) using human histone as substrate measured after 60 mins in presence of [3H]-acetyl-CoA by microbeta counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed