BDBM50400734 CHEMBL1591531

SMILES [H]/N=C(/N)\SCCCn1cc(c2c1cccc2)C3=C(C(=O)NC3=O)c4cn(c5c4cccc5)C

InChI Key InChIKey=DSXXEELGXBCYNQ-UHFFFAOYSA-N

Data  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50400734   

LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant SIRT3 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHomeodomain-interacting protein kinase 1(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50400734(CHEMBL1591531)
Affinity DataIC50: 0.367nMAssay Description:Inhibition of HIPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed